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CFLAR Antibody

Product Specifications

Background

CFLAR might contribute to the carcinogenesis and aggressiveness of endometrial carcinoma and might be a useful prognostic factor in the tumor. CFLAR is specially overexpressed in colon cancers and it might contribute to carcinogenesis of normal colonic mucosa.

NCBI Gene ID

8837

Swiss Prot

O15519

Accession Number

NP_003870

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CFLAR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction, Immunology, Apoptosis

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CFLAR antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

55 kDa

Applications Notes

CFLAR antibody can be used for detection of CFLAR by ELISA at 1:312500. CFLAR antibody can be used for detection of CFLAR by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

CFLAR

NCBI Official Name

CASP8 and FADD-like apoptosis regulator

NCBI Organism

Homo sapiens

Background Reference 01

Kondo, G., et al., (2005) Oncol Rep. 14 (5), 1215-22.

Other Product Names

CFLAR, CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1

Tested Applications

ELISA, WB

Protein ID

187608571

Physical Properties

Liquid

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