CBX2 Antibody
Product Specifications
Background
CBX2 Contains 1 A.T hook DNA-binding domain and 1 chromo domain. CBX2 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
NCBI Gene ID
84733
Swiss Prot
Q14781
Accession Number
NP_005180
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CBX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1301 - Human Heart Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CBX2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=30-735
Calculated Molecular Weight
56 kDa
Applications Notes
CBX2 antibody can be used for detection of CBX2 by ELISA at 1:1562500. CBX2 antibody can be used for detection of CBX2 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CBX2
NCBI Official Name
Chromobox homolog 2
NCBI Organism
Homo sapiens
Background Reference 01
Garcia, E., (1999) EMBO J. 18 (12), 3404-3418.
Other Product Names
CBX2, CDCA6, M33, MGC10561, SRXY5
Tested Applications
ELISA, WB
Protein ID
61743963
Physical Properties
Liquid
Curated Selection
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