CDT1 Antibody
Product Specifications
Background
CDT1 cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. It binds DNA in a sequence-, strand-, and conformation-independent manner and is a potential oncogene.
NCBI Gene ID
81620
Swiss Prot
Q9H211
Accession Number
NP_112190
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CDT1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
60 kDa
Applications Notes
CDT1 antibody can be used for detection of CDT1 by ELISA at 1:62500. CDT1 antibody can be used for detection of CDT1 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CDT1
NCBI Official Name
Chromatin licensing and DNA replication factor 1
NCBI Organism
Homo sapiens
Background Reference 01
Hu, J. (2006) J. Biol. Chem. 281 (7), 3753-3756.
Other Product Names
CDT1, DUP, RIS2
Tested Applications
ELISA, WB
Protein ID
188497689
Physical Properties
Liquid
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