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STS Antibody

Product Specifications

Background

STS catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in its gene are known to cause X-linked ichthyosisThe protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI) .

NCBI Gene ID

412

Swiss Prot

P08842

Accession Number

NP_000342

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human STS.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Cancer, Signal Transduction

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1309 - Human Placenta Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store STS antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

64 kDa

Applications Notes

STS antibody can be used for detection of STS by ELISA at 1:312500. STS antibody can be used for detection of STS by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

STS

NCBI Official Name

Steroid sulfatase (microsomal), isozyme S

NCBI Organism

Homo sapiens

Background Reference 01

Kimura, K., (2006) Genome Res. 16 (1), 55-65.

Other Product Names

STS, ARSC, ARSC1, ASC, ES, SSDD, XLI

Tested Applications

ELISA, WB

Protein ID

53831991

Physical Properties

Liquid

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