SLC13A3 Antibody
Product Specifications
Background
Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. SLC13A3 represents the high-affinity form.Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.
NCBI Gene ID
64849
Swiss Prot
Q8WWT9
Accession Number
NP_001011554
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC13A3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLC13A3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
61 kDa, 67 kDa
Applications Notes
SLC13A3 antibody can be used for detection of SLC13A3 by ELISA at 1:312500. SLC13A3 antibody can be used for detection of SLC13A3 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SLC13A3
NCBI Official Name
Solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
NCBI Organism
Homo sapiens
Background Reference 01
Bai, X., (2006) J. Cell. Physiol. 206 (3), 821-830.
Other Product Names
SLC13A3, NADC3, SDCT2
Tested Applications
ELISA, WB, IHC
Protein ID
58761541
Physical Properties
Liquid
Curated Selection
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