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CPSF6 Antibody

Product Specifications

Background

CPSF6 is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides.The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.

NCBI Gene ID

11052

Swiss Prot

Q16630

Accession Number

NP_008938

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPSF6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CPSF6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

61 kDa

Applications Notes

CPSF6 antibody can be used for detection of CPSF6 by ELISA at 1:1562500. CPSF6 antibody can be used for detection of CPSF6 by western blot at 0.3125 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

CPSF6

NCBI Official Name

Cleavage and polyadenylation specific factor 6, 68kDa

NCBI Organism

Homo sapiens

Background Reference 01

Rual, J.F., (2005) Nature 437 (7062), 1173-1178.

Other Product Names

CPSF6, CFIM, CFIM68, HPBRII-4, HPBRII-7

Tested Applications

ELISA, WB, IHC

Protein ID

162329583

Physical Properties

Liquid

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