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TP73 Antibody

Product Specifications

Background

TP73 belongs to the p53 family. It participates in the apoptotic response to DNA damage. When overproduced, it activates transcription from p53-responsive promoters and induces apoptosis. TP53 may be a tumor suppressor protein.

NCBI Gene ID

7161

Swiss Prot

O15350-2

Accession Number

CAA72219

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TP73.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cell Cycle, Cancer, Apoptosis

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TP73 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

55 kDa, 70 kDa

Applications Notes

TP73 antibody can be used for detection of TP73 by ELISA at 1:312500. TP73 antibody can be used for detection of TP73 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

TP73

NCBI Official Name

Tumor protein p73

NCBI Organism

Homo sapiens

Background Reference 01

Kaghad, M., (1997) Cell 90 (4), 809-819.

Other Product Names

TP73, P73

Tested Applications

ELISA, WB

Protein ID

2370177

Physical Properties

Liquid

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