RCV1 Antibody
Product Specifications
Background
RCV1 is a member of the recoverin family of neuronal calcium sensors. RCV1 contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.The protein encoded by this gene contains four calcium-binding EF-hand domains and belongs to the recoverin family of neuronal calcium sensors. Recoverin may prolong the termination of the phototransduction cascade by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy; an autoimmune disease of the retina caused by a tumor in another tissue.
NCBI Gene ID
5957
Swiss Prot
Q53XL0
Accession Number
NP_002894
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RCV1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RCV1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=28-817
Calculated Molecular Weight
23 kDa
Applications Notes
RCV1 antibody can be used for detection of RCV1 by ELISA at 1:312500. RCV1 antibody can be used for detection of RCV1 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RCVRN
NCBI Official Name
Recoverin
NCBI Organism
Homo sapiens
Background Reference 01
Miyagawa, Y., et al., (2003) Biochem. Biophys. Res. Commun. 300 (3), 669-673.
Other Product Names
RCV1, RCV1
Tested Applications
ELISA, WB
Protein ID
4506459
Physical Properties
Liquid
Curated Selection
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