IRF4 Antibody
Product Specifications
Background
IFN regulatory factor (IRF) -4 is a lymphoid/myeloid-restricted member of the IRF transcription factor family that plays an essential role in the homeostasis and function of mature lymphocytes. IRF-4 expression is tightly regulated in resting primary T cells and is transiently induced at the mRNA and protein levels after activation by Ag-mimetic stimuli such as TCR cross-linking or treatment with phorbol ester and calcium ionophore (PMA/ionomycin) .
NCBI Gene ID
3662
Swiss Prot
Q15306
Accession Number
NP_002451
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IRF4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Signal Transduction, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store IRF4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=28-806
Calculated Molecular Weight
52 kDa
Applications Notes
IRF4 antibody can be used for detection of IRF4 by ELISA at 1:312500. IRF4 antibody can be used for detection of IRF4 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
IRF4
NCBI Official Name
Interferon regulatory factor 4
NCBI Organism
Homo sapiens
Background Reference 01
Lehtonen, A., (2005) J. Immunol. 175 (10), 6570-6579.
Other Product Names
IRF4, LSIRF, MUM1, NF-EM5
Tested Applications
ELISA, WB, IHC
Protein ID
167555104
Physical Properties
Liquid
Curated Selection
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