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JUN Antibody

Product Specifications

Background

JUN gene is the putative transforming gene of avian sarcoma virus 17. I JUN is highly similar to the viral protein, and interacts directly with specific target DNA sequences to regulate gene expression. JUN gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.

NCBI Gene ID

3725

Swiss Prot

P05412

Accession Number

NP_002219

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human JUN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cancer , Inflammasomes

Purification

Antibody is purified by protein A chromatography method.

Positive Control

293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store JUN antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

36 kDa

Applications Notes

JUN antibody can be used for detection of JUN by ELISA at 1:312500. JUN antibody can be used for detection of JUN by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

JUN

NCBI Official Name

Jun proto-oncogene

NCBI Organism

Homo sapiens

Background Reference 01

Grau, R., et al., (2006) Biochem. J. 395 (1), 81-88.

Other Product Names

JUN, AP1, AP-1, c-Jun

Tested Applications

ELISA, WB

Protein ID

4758616

Physical Properties

Liquid

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