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VDAC2 Antibody

Product Specifications

Background

VDAC2 forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.

NCBI Gene ID

7417

Swiss Prot

P45880-5

Accession Number

NP_003366

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human VDAC2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Tranfected 293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store VDAC2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

32 kDa, 31 kDa, 31 kDa

Applications Notes

VDAC2 antibody can be used for detection of VDAC2 by ELISA at 1:312500. VDAC2 antibody can be used for detection of VDAC2 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

VDAC2

NCBI Official Name

Voltage-dependent anion channel 2

NCBI Organism

Homo sapiens

Background Reference 01

Chandra, D., (2005) J. Biol. Chem. 280 (19), 19051-19061.

Other Product Names

VDAC2, RP11-375G3.1, FLJ23841, POR

Tested Applications

ELISA, WB

Protein ID

42476281

Physical Properties

Liquid

Curated Selection

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