THRA Antibody
Product Specifications
Background
The THRA gene encodes a protein that is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone.
NCBI Gene ID
7067
Swiss Prot
P10827
Accession Number
NP_003241
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human THRA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store THRA antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
55 kDa, 47 kDa
Applications Notes
THRA antibody can be used for detection of THRA by ELISA at 1:62500. THRA antibody can be used for detection of THRA by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
THRA
NCBI Official Name
Thyroid hormone receptor, alpha
NCBI Organism
Homo sapiens
Background Reference 01
DeLong, L.J., et al., (2004) J. Biol. Chem. 279 (15), 15356-15367.
Other Product Names
THRA, AR7, EAR7, ERBA, CHNG6, ERBA1, NR1A1, THRA1, THRA2, ERB-T-1, c-ERBA-1
Tested Applications
ELISA, WB, IHC
Protein ID
20127452
Physical Properties
Liquid
Curated Selection
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