RBAK Antibody
Product Specifications
Background
RBAK encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif.This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif.
NCBI Gene ID
57786
Swiss Prot
Q9NYW8
Accession Number
NP_066986
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RBAK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
NTERA2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RBAK antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
83 kDa
Applications Notes
RBAK antibody can be used for detection of RBAK by ELISA at 1:1562500. RBAK antibody can be used for detection of RBAK by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RBAK
NCBI Official Name
RB-associated KRAB zinc finger
NCBI Organism
Homo sapiens
Background Reference 01
Jeske, Y.W., (2008) Clin. Exp. Pharmacol. Physiol. 35 (4), 380-385.
Other Product Names
RBAK, ZNF769
Tested Applications
ELISA, WB
Protein ID
13430850
Physical Properties
Liquid
Curated Selection
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