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RBAK Antibody

Product Specifications

Background

RBAK encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif.This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif.

NCBI Gene ID

57786

Swiss Prot

Q9NYW8

Accession Number

NP_066986

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RBAK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

NTERA2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RBAK antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

83 kDa

Applications Notes

RBAK antibody can be used for detection of RBAK by ELISA at 1:1562500. RBAK antibody can be used for detection of RBAK by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

RBAK

NCBI Official Name

RB-associated KRAB zinc finger

NCBI Organism

Homo sapiens

Background Reference 01

Jeske, Y.W., (2008) Clin. Exp. Pharmacol. Physiol. 35 (4), 380-385.

Other Product Names

RBAK, ZNF769

Tested Applications

ELISA, WB

Protein ID

13430850

Physical Properties

Liquid

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