CREB3 Antibody
Product Specifications
Background
CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined.
NCBI Gene ID
10488
Swiss Prot
Q5TCV1
Accession Number
NP_006359
Host
Rabbit
Reactivity
Human, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CREB3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CREB3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
41 kDa
Applications Notes
CREB3 antibody can be used for detection of CREB3 by ELISA at 1:312500. CREB3 antibody can be used for detection of CREB3 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CREB3
NCBI Official Name
CAMP responsive element binding protein 3
NCBI Organism
Homo sapiens
Background Reference 01
Misra, V., et al., (2005) J. Biol. Chem. 280 (15), 15257-15266.
Other Product Names
CREB3, LZIP, LUMAN
Tested Applications
ELISA, WB
Protein ID
22219462
Physical Properties
Liquid
Curated Selection
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