OLIG2 Antibody
Product Specifications
Background
OLIG2 is a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. OLIG2 is an essential regulator of ventral neuroectodermal progenitor cell fate. It is associated with T-cell acute lymphoblastic leukemia due to a chromosomal translocation t (14;21) (q11.2; q22) . OLIG2 might play a role in learning deficits associated with Down syndrome.
NCBI Gene ID
10215
Swiss Prot
Q13516
Accession Number
NP_005797
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human OLIG2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store OLIG2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
32 kDa
Applications Notes
OLIG2 antibody can be used for detection of OLIG2 by ELISA at 1:312500. OLIG2 antibody can be used for detection of OLIG2 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
OLIG2
NCBI Official Name
Oligodendrocyte lineage transcription factor 2
NCBI Organism
Homo sapiens
Background Reference 01
Sun, T., et al., (2006) Dev. Biol. 292 (1), 152-164.
Other Product Names
OLIG2, BHLHB1, OLIGO2, RACK17, PRKCBP2, bHLHe19
Tested Applications
ELISA, WB
Protein ID
17978475
Physical Properties
Liquid
Curated Selection
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