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CDK5 Antibody

Product Specifications

Background

CDK5 is probably involved in the control of the cell cycle. It interacts with D1 and D3-type G1 cyclins. The protein can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. And it is also thought to interacts with p35 which activates the kinase.

NCBI Gene ID

1020

Swiss Prot

Q00535

Accession Number

NP_004926

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDK5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cell Cycle, Cancer, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

721_B Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CDK5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

33 kDa

Applications Notes

CDK5 antibody can be used for detection of CDK5 by ELISA at 1:62500. CDK5 antibody can be used for detection of CDK5 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

CDK5

NCBI Official Name

Cyclin-dependent kinase 5

NCBI Organism

Homo sapiens

Background Reference 01

Liu, R., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (21), 7570-7575.

Other Product Names

CDK5, PSSALRE

Tested Applications

ELISA, WB

Protein ID

4826675

Physical Properties

Liquid

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