ACO2 Antibody
Product Specifications
Background
ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
50
Swiss Prot
Q99798
Accession Number
NP_001089
Host
Rabbit
Reactivity
Human, Mouse, Rat, C. elegans
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ACO2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
721_B Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ACO2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
82 kDa
Applications Notes
ACO2 antibody can be used for detection of ACO2 by ELISA at 1:312500. ACO2 antibody can be used for detection of ACO2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ACO2
NCBI Official Name
Aconitase 2, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Yu, Z., (2006) Prostate 66 (10), 1061-1069.
Other Product Names
ACO2, ACONM, MGC20605, MGC33908, ICRD
Tested Applications
ELISA, WB
Protein ID
4501867
Physical Properties
Liquid
Curated Selection
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