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ACO2 Antibody

Product Specifications

Background

ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

NCBI Gene ID

50

Swiss Prot

Q99798

Accession Number

NP_001089

Host

Rabbit

Reactivity

Human, Mouse, Rat, C. elegans

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ACO2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

721_B Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ACO2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

82 kDa

Applications Notes

ACO2 antibody can be used for detection of ACO2 by ELISA at 1:312500. ACO2 antibody can be used for detection of ACO2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

ACO2

NCBI Official Name

Aconitase 2, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Yu, Z., (2006) Prostate 66 (10), 1061-1069.

Other Product Names

ACO2, ACONM, MGC20605, MGC33908, ICRD

Tested Applications

ELISA, WB

Protein ID

4501867

Physical Properties

Liquid

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