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MAGEA4 Antibody

Product Specifications

Background

MAGEA4 is a member of the MAGEA family. The members of this family are proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.

NCBI Gene ID

4103

Swiss Prot

P43358

Accession Number

NP_001011548

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAGEA4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MAGEA4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

35 kDa

Applications Notes

MAGEA4 antibody can be used for detection of MAGEA4 by ELISA at 1:312500. MAGEA4 antibody can be used for detection of MAGEA4 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

MAGEA4

NCBI Official Name

Melanoma antigen family A, 4

NCBI Organism

Homo sapiens

Background Reference 01

Ries, J., (2008) J. Oral Pathol. Med. 37 (2), 88-93.

Other Product Names

MAGEA4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, MGC21336, CT1.4

Tested Applications

ELISA, WB

Protein ID

58530867

Physical Properties

Liquid

Curated Selection

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