MAGEA4 Antibody
Product Specifications
Background
MAGEA4 is a member of the MAGEA family. The members of this family are proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene.
NCBI Gene ID
4103
Swiss Prot
P43358
Accession Number
NP_001011548
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAGEA4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MAGEA4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
35 kDa
Applications Notes
MAGEA4 antibody can be used for detection of MAGEA4 by ELISA at 1:312500. MAGEA4 antibody can be used for detection of MAGEA4 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MAGEA4
NCBI Official Name
Melanoma antigen family A, 4
NCBI Organism
Homo sapiens
Background Reference 01
Ries, J., (2008) J. Oral Pathol. Med. 37 (2), 88-93.
Other Product Names
MAGEA4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, MGC21336, CT1.4
Tested Applications
ELISA, WB
Protein ID
58530867
Physical Properties
Liquid
Curated Selection
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