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CDC42EP5 Antibody

Product Specifications

Background

CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined.CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined.

NCBI Gene ID

148170

Swiss Prot

Q6NZY7

Accession Number

NP_659494

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDC42EP5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Tranfected 293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CDC42EP5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

15 kDa

Applications Notes

CDC42EP5 antibody can be used for detection of CDC42EP5 by ELISA at 1:312500. CDC42EP5 antibody can be used for detection of CDC42EP5 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

CDC42EP5

NCBI Official Name

CDC42 effector protein (Rho GTPase binding) 5

NCBI Organism

Homo sapiens

Background Reference 01

Joberty, G., (2001) Nat. Cell Biol. 3 (10), 861-866.

Other Product Names

CDC42EP5, Borg3, CEP5, MGC21945, MGC71153

Tested Applications

ELISA, WB

Protein ID

30089966

Physical Properties

Liquid

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