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INTS4 Antibody

Product Specifications

Background

INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2) .INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]) .

NCBI Gene ID

92105

Swiss Prot

Q96HW7

Accession Number

NP_291025

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human INTS4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1201 - HeLa Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store INTS4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

108 kDa

Applications Notes

INTS4 antibody can be used for detection of INTS4 by ELISA at 1:12500. INTS4 antibody can be used for detection of INTS4 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

INTS4

NCBI Official Name

Integrator complex subunit 4

NCBI Organism

Homo sapiens

Background Reference 01

Baillat, D., (2005) Cell 123 (2), 265-276.

Other Product Names

INTS4, INT4, MGC16733, MST093

Tested Applications

ELISA, WB

Protein ID

50086624

Physical Properties

Liquid

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