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UGCGL2 Antibody

Product Specifications

Background

UGCGL2 recognizes glycoproteins with minor folding defects. UGCGL2 reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.

NCBI Gene ID

55757

Swiss Prot

Q9NYU1

Accession Number

NP_064506

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UGCGL2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store UGCGL2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

172 kDa

Applications Notes

UGCGL2 antibody can be used for detection of UGCGL2 by ELISA at 1:12500. UGCGL2 antibody can be used for detection of UGCGL2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

UGGT2

NCBI Official Name

UDP-glucose glycoprotein glucosyltransferase 2

NCBI Organism

Homo sapiens

Background Reference 01

Arnold, S.M. (2003) J. Biol. Chem. 278 (44), 43320-43328.

Other Product Names

UGCGL2, FLJ10873, FLJ11485, HUGT2, MGC117360, MGC150689, MGC87276, UGT2, UGCGL2

Tested Applications

ELISA, WB

Protein ID

238859593

Physical Properties

Liquid

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