EIF3E Antibody
Product Specifications
Background
EIF3E belongs to the eIF-3 subunit E family.It is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. EIF3E is required for nonsense-mediated mRNA decay (NMD) ; It may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. The protein may interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
NCBI Gene ID
3646
Swiss Prot
P60228
Accession Number
NP_001559
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EIF3E.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store EIF3E antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=26-291
Calculated Molecular Weight
52 kDa
Applications Notes
EIF3E antibody can be used for detection of EIF3E by ELISA at 1:62500. EIF3E antibody can be used for detection of EIF3E by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
EIF3E
NCBI Official Name
Eukaryotic translation initiation factor 3, subunit E
NCBI Organism
Homo sapiens
Background Reference 01
Buchsbaum, S., (2007) Oncogene 26 (35), 5132-5144.
Other Product Names
EIF3E, EIF3-P48, EIF3S6, INT6, eIF3-p46
Tested Applications
ELISA, WB
Protein ID
4503521
Physical Properties
Liquid
Curated Selection
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