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HAL Antibody

Product Specifications

Background

HAL is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. HAL defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids.

NCBI Gene ID

3034

Swiss Prot

P42357

Accession Number

NP_002099

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HAL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

721_B Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HAL antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

72 kDa

Applications Notes

HAL antibody can be used for detection of HAL by ELISA at 1:1562500. HAL antibody can be used for detection of HAL by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

HAL

NCBI Official Name

Histidine ammonia-lyase

NCBI Organism

Homo sapiens

Background Reference 01

Aleman, G., Am. J. Physiol. Endocrinol. Metab. 289 (1), E172-E179 (2005) .

Other Product Names

HAL, HIS, HSTD, histidase

Tested Applications

ELISA, WB

Protein ID

4504333

Physical Properties

Liquid

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