HSD11B2 Antibody

Product Specifications

Background

HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

NCBI Gene ID

3291

Swiss Prot

P80365

Accession Number

NP_000187

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HSD11B2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HSD11B2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

45 kDa

Applications Notes

HSD11B2 antibody can be used for detection of HSD11B2 by ELISA at 1:62500. HSD11B2 antibody can be used for detection of HSD11B2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.