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SPIC Antibody

Product Specifications

Background

This protein Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression

NCBI Gene ID

121599

Swiss Prot

Q8N5J4

Accession Number

NP_689536

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SPIC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Tranfected 293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SPIC antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

29 kDa

Applications Notes

SPIC antibody can be used for detection of SPIC by ELISA at 1:62500. SPIC antibody can be used for detection of SPIC by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

SPIC

NCBI Official Name

Spi-C transcription factor (Spi-1/PU.1 related)

NCBI Organism

Homo sapiens

Background Reference 01

Carlsson, R., (2006) Biochem. Biophys. Res. Commun. 344 (4), 1155-1160.

Other Product Names

SPIC, MGC40611, SPI-C

Tested Applications

ELISA, WB

Protein ID

22748707

Physical Properties

Liquid

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