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LASS5 Antibody

Product Specifications

Background

LASS5 may be either a bona fide (dihydro) ceramide synthase or a modulator of its activity. When it is overexpressed in cells it is involved in the production of sphingolipids containing mainly only one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner.

NCBI Gene ID

91012

Swiss Prot

Q8N5B7

Accession Number

NP_671723

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LASS5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Membrane

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10408 - Fetal Kidney Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store LASS5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

46 kDa

Applications Notes

LASS5 antibody can be used for detection of LASS5 by ELISA at 1:12500. LASS5 antibody can be used for detection of LASS5 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

CERS5

NCBI Official Name

Ceramide synthase 5

NCBI Organism

Homo sapiens

Background Reference 01

Kitatani, K., (2006) J. Biol. Chem. 281 (48), 36793-36802.

Other Product Names

LASS5, CerS5, FLJ25304, MGC45411, Trh4, LASS5

Tested Applications

ELISA, WB

Protein ID

22218345

Physical Properties

Liquid

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