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SLC18A1 Antibody

Product Specifications

Background

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazineThe vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]) . See also SLC18A2 (MIM 193001) .

NCBI Gene ID

6570

Swiss Prot

P54219

Accession Number

NP_003044

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC18A1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLC18A1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

56 kDa

Applications Notes

SLC18A1 antibody can be used for detection of SLC18A1 by ELISA at 1:62500. SLC18A1 antibody can be used for detection of SLC18A1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

SLC18A1

NCBI Official Name

Solute carrier family 18 (vesicular monoamine transporter), member 1

NCBI Organism

Homo sapiens

Background Reference 01

Lohoff, F.W., (er) Neuropsychobiology 57 (1-2), 55-60 (2008) In press.

Other Product Names

SLC18A1, CGAT, VAT1, VMAT1

Tested Applications

ELISA, WB

Protein ID

4506987

Physical Properties

Liquid

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