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HTR3E Antibody

Product Specifications

Background

HTR3E belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.

NCBI Gene ID

285242

Swiss Prot

A5X5Y0

Accession Number

NP_872395

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR3E.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10407 - Fetal Heart Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HTR3E antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

53 kDa

Applications Notes

HTR3E antibody can be used for detection of HTR3E by ELISA at 1:312500. HTR3E antibody can be used for detection of HTR3E by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

HTR3E

NCBI Official Name

5-hydroxytryptamine (serotonin) receptor 3E, ionotropic

NCBI Organism

Homo sapiens

Background Reference 01

Peters, J.A., Biochem. Soc. Trans. 32 (PT3), 547-552 (2004) .

Other Product Names

HTR3E, 5-HT3c1, MGC120035, MGC120036, MGC120037, 5-HT3E, 5-HT3-E

Tested Applications

ELISA, WB

Protein ID

47519913

Physical Properties

Liquid

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