TCF7L2 Antibody
Product Specifications
Background
The TCL7L2 is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. suggested that TCL7L2 acts through regulation of proglucagon through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway. The TCL7L2 gene product is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. (2005) [PubMed 15525634] suggested that TCL7L2 acts through regulation of proglucagon (MIM 138030) through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway.
NCBI Gene ID
6934
Swiss Prot
Q6FHW4
Accession Number
NP_110383
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCF7L2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TCF7L2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=25-138
Calculated Molecular Weight
65 kDa
Applications Notes
TCF7L2 antibody can be used for detection of TCF7L2 by ELISA at 1:2500. TCF7L2 antibody can be used for detection of TCF7L2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TCF7L2
NCBI Official Name
Transcription factor 7-like 2 (T-cell specific, HMG-box)
NCBI Organism
Homo sapiens
Background Reference 01
Ren, Q., (2008) Diabetologia 51 (7), 1146-1152.
Other Product Names
TCF7L2, TCF-4, TCF4
Tested Applications
ELISA, WB
Protein ID
170014696
Physical Properties
Liquid
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