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PCBD1 Antibody

Product Specifications

Background

PCBD1 is pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1) .This gene encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1) . Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

NCBI Gene ID

5092

Swiss Prot

P61457

Accession Number

NP_000272

Host

Rabbit

Reactivity

Human, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCBD1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10409 - Fetal Liver Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PCBD1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

12 kDa

Applications Notes

PCBD1 antibody can be used for detection of PCBD1 by ELISA at 1:312500. PCBD1 antibody can be used for detection of PCBD1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

PCBD1

NCBI Official Name

Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha

NCBI Organism

Homo sapiens

Background Reference 01

Hevel, J.M., (2006) Mol. Genet. Metab. 88 (1), 38-46.

Other Product Names

PCBD1, DCOH, PCBD, PCD, PHS

Tested Applications

ELISA, WB

Protein ID

4557831

Physical Properties

Liquid

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