ERC1 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t (10;12) (q11; p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

23085

Swiss Prot

Q8IUD2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 700-850 of human ERC1 (NP_829884.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Immunology, Neuroscience

Purification

Affinity purification

Positive Control

HepG2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 130 120kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

ERC1

Positive Control 2

Jurkat

Positive Control 3

NIH/3T3

Positive Control 4

Rat brain

NCBI Official Name

ELKS/RAB6-interacting/CAST family member 1

NCBI Organism

Homo sapiens

Other Product Names

ERC1, ELKS/RAB6-interacting/CAST family member 1, Cast2, ELKS, KIAA1081, MGC12974, RAB6IP2, RAB6 interacting protein 2, RAB6-interacting protein 2, Rab6-interacting protein 2