LLGL2 Antibody
Product Specifications
Background
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC) . In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI Gene ID
217325
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 620-819 of mouse LLGL2 (NP_663413.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 113kDa
Fragment
IgG
Symbol
LLGL2
Positive Control 2
Mouse liver
Positive Control 3
Rat liver
NCBI Official Name
LLGL2 scribble cell polarity complex component
NCBI Organism
Mus musculus
Other Product Names
9130006H11Rik, Llglh2, lethal (2) giant larvae protein homolog 2, lethal giant larvae-like protein 2
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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