ABCE1 Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
6059
Swiss Prot
P61221
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 320-599 of human ABCE1 (NP_002931.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=23-432
Calculated Molecular Weight
Observed: 67kDa
Fragment
IgG
Symbol
ABCE1
Positive Control 2
Jurkat
Positive Control 3
293T
Positive Control 4
HeLa
Positive Control 5
Mouse liver
NCBI Official Name
ATP-binding cassette, sub-family E (OABP), member 1
NCBI Organism
Homo sapiens
Other Product Names
ABCE1, RLI, OABP, ABC38, RNS4I, RNASEL1, RNASELI, ATP-binding cassette, sub-family E (OABP), member 1, RNase L inhibitor, ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) inhibitor, HP68, OK/SW-cl.40
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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