PLCB2 Antibody

Product Specifications

Background

The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.

NCBI Gene ID

5330

Swiss Prot

Q00722

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human PLCB2 (NP_001271228.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 150kDa

Fragment

IgG

Symbol

PLCB2

Positive Control 2

U-937

Positive Control 3

Mouse thymus

Positive Control 4

Mouse liver

Positive Control 5

Rat liver

NCBI Official Name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2

NCBI Organism

Homo sapiens

Other Product Names

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2, Phosphoinositide phospholipase C-beta-2, Phospholipase C-beta-2, PLC-beta-2, PLCB2

Tested Applications

WB, IHC

Physical Properties

Liquid

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