CFL2 Antibody
Product Specifications
Background
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
1073
Swiss Prot
Q9Y281
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human CFL2 (NP_068733.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 18kDa
Fragment
IgG
Symbol
CFL2
Positive Control 2
HeLa
Positive Control 3
Raji
Positive Control 4
NCI-H460
Positive Control 5
Mouse heart
Positive Control 6
Mouse skeletal muscle
NCBI Official Name
Cofilin 2 (muscle)
NCBI Organism
Homo sapiens
Other Product Names
Cofilin 2, NEM7, CFL2, HGNC:1875, cofilin 2 (muscle)
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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