OPA3 Antibody

Product Specifications

Background

The mouse ortholog of this protein co-purifies with the mitochondrial inner membrane. Mutations in this gene have been shown to result in 3-methylglutaconic aciduria type III and autosomal dominant optic atrophy and cataract. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

80207

Swiss Prot

Q9H6K4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 25-179 of human OPA3 (NP_079412.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Affinity purification

Positive Control

Mouse eye

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 20kDa

Fragment

IgG

Symbol

OPA3

Positive Control 2

Rat eye

NCBI Official Name

Outer mitochondrial membrane lipid metabolism regulator OPA3

NCBI Organism

Homo sapiens

Other Product Names

MGA3, optic atrophy 3 protein, OPA3 outer mitochondrial membrane lipid metabolism regulator, Optic atrophy 3 (Iraqi-Jewish 'optic atrophy plus'), optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)