VPS37A Antibody
Product Specifications
Background
This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.
NCBI Gene ID
137492
Swiss Prot
Q8NEZ2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 224-397 of human VPS37A (NP_689628.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 44kDa
Fragment
IgG
Symbol
VPS37A
Positive Control 2
Jurkat
Positive Control 3
HepG2
NCBI Official Name
Vacuolar protein sorting 37 homolog A (S. cerevisiae)
NCBI Organism
Homo sapiens
Other Product Names
VPS37A, FLJ32642, FLJ42616, HCRP1, PQBP2, SPG53
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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