TSEN2 Antibody
Product Specifications
Background
This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
80746
Swiss Prot
Q8NCE0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human TSEN2 (NP_079541.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 53kDa
Fragment
IgG
Symbol
TSEN2
Positive Control 2
HeLa
Positive Control 3
A-549
Positive Control 4
Mouse heart
Positive Control 5
Mouse brain
Positive Control 6
Rat heart
NCBI Official Name
TRNA-splicing endonuclease subunit Sen2
NCBI Organism
Homo sapiens
Other Product Names
TRNA-splicing endonuclease subunit Sen2, tRNA-intron endonuclease Sen2, HsSen2, TSEN2, SEN2
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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