DARS2 Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL) .

NCBI Gene ID

55157

Swiss Prot

Q6PI48

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 406-645 of human DARS2 (NP_060592.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

NCI-H460

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 74kDa

Fragment

IgG

Symbol

DARS2

Positive Control 2

U-251MG

Positive Control 3

MCF7

Positive Control 4

BT-474

Positive Control 5

Mouse liver

Positive Control 6

Mouse heart

NCBI Official Name

Aspartyl-tRNA synthetase 2, mitochondrial

NCBI Organism

Homo sapiens

Other Product Names

ASPRS, LBSL, MT-ASPRS, mtAspRS, aspartate--tRNA ligase, mitochondrial, aspartate tRNA ligase 2, mitochondrial, aspartyl-tRNA synthetase, mitochondrial