ICK Antibody

Product Specifications

Background

Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.

NCBI Gene ID

22858

Swiss Prot

Q9UPZ9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ICK (NP_057597.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 71kDa

Fragment

IgG

Symbol

ICK

Positive Control 2

SW620

Positive Control 3

Mouse liver

Positive Control 4

Mouse lung

Positive Control 5

Mouse brain

NCBI Official Name

Intestinal cell kinase

NCBI Organism

Homo sapiens

Other Product Names

ECO, EJM1LCK2, MRK, serine/threonine-protein kinase ICK, MAK-related kinase, hICK, intestinal cell (MAK-like) kinase, laryngeal cancer kinase 2, serine/threonine protein kinase