SGCD Antibody

Product Specifications

Background

The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC) . DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

NCBI Gene ID

6444

Swiss Prot

Q92629

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 61-290 of human SGCD (NP_000328.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

Jurkat

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 37kDa

Fragment

IgG

Symbol

SGCD

Positive Control 2

THP-1

Positive Control 3

Mouse heart

Positive Control 4

Mouse skeletal muscle

Positive Control 5

Rat heart

Positive Control 6

Rat skeletal muscle

NCBI Official Name

Sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)

NCBI Organism

Homo sapiens

Other Product Names

Dystrophin associated, delta-sarcoglycan, delta-SG, 35kD dystrophin-associated glycoprotein, SGD, SGCDP, SG-delta, MGC22567, DAGD, CMD1L, 35DAG, sarcoglycan, delta (35kDa dystrophin-associated glycoprotein), SGCD