MAP2K5 Antibody

Product Specifications

Background

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs) . The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

NCBI Gene ID

5607

Swiss Prot

Q13163

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MAP2K5 (NP_660143.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology, Signal Transduction

Purification

Affinity purification

Positive Control

NCI-H460

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 50kDa

Fragment

IgG

Symbol

MAP2K5

Positive Control 2

BT-474

Positive Control 3

Mouse liver

Positive Control 4

Rat liver

Positive Control 5

Rat kidney

NCBI Official Name

Dual specificity mitogen-activated protein kinase kinase 5

NCBI Organism

Homo sapiens

Other Product Names

Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5, MEK 5, MAP2K5, MEK5, MKK5, PRKMK5

Tested Applications

WB, IHC, IF

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RD21248F-01 25 µg

Purified Anti-Mouse CD8a Antibody

Ask

View Details

RD21248F-02 100 µg

Purified Anti-Mouse CD8a Antibody

Ask

View Details

ABT-DOA-K340~348 1 Test

Multi-2 ~ 10 Drug Cup W/Indicator & Alcohol

Ask

View Details

G3060-01-01 10 g

D-Glucuronic Acid, Sodium Salt Monohydrate (Sodium D-Glucuronate)

Ask

View Details

G3060-01-02 25 g

D-Glucuronic Acid, Sodium Salt Monohydrate (Sodium D-Glucuronate)

Ask

View Details

G3060-01-03 100 g

D-Glucuronic Acid, Sodium Salt Monohydrate (Sodium D-Glucuronate)

Ask

View Details