SRGN Antibody

Product Specifications

Background

This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene.

NCBI Gene ID

5552

Swiss Prot

P10124

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 28-158 of human SRGN (NP_002718.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Obesity, Signal Transduction

Purification

Affinity purification

Positive Control

THP-1

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 17kDa

Fragment

IgG

Symbol

SRGN

NCBI Official Name

Serglycin

NCBI Organism

Homo sapiens

Other Product Names

Serglycin, Hematopoietic proteoglycan core protein, Platelet proteoglycan core protein, PPG, Secretory granule proteoglycan core protein, SRGN, PRG, PRG1