MYO1C Antibody
Product Specifications
Background
This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.
NCBI Gene ID
4641
Swiss Prot
O00159
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 769-1028 of human MYO1C (NP_203693.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
HT-29
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=22-567
Calculated Molecular Weight
Observed: 122kDa
Fragment
IgG
Symbol
MYO1C
Positive Control 2
SKOV3
Positive Control 3
Mouse lung
Positive Control 4
Rat lung
NCBI Official Name
Unconventional myosin-Ic
NCBI Organism
Homo sapiens
Other Product Names
Unconventional myosin-Ic, Myosin I beta, MMI-beta, MMIb, MYO1C
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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