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CRY2 Antibody

Product Specifications

Background

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

1408

Swiss Prot

Q49AN0

Host

Rabbit

Reactivity

Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 455-614 of human CRY2 (NP_066940.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Affinity purification

Positive Control

Rat brain

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 67kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

CRY2

NCBI Official Name

Cryptochrome circadian clock 2

NCBI Organism

Homo sapiens

Other Product Names

CRY2, Cryptochrome-2, KIAA0658, Growth-inhibiting protein 37, Photolyase-like 2, PHLL2, HCRY2

Tested Applications

WB

Physical Properties

Liquid

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