RECK Antibody
Product Specifications
Background
The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
8434
Swiss Prot
O95980
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 110-210 of human RECK (NP_066934.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 106kDa
Fragment
IgG
Symbol
RECK
Positive Control 2
MCF-7
Positive Control 3
H460
Positive Control 4
Mouse lung
Positive Control 5
Mouse kidney
NCBI Official Name
Reversion-inducing cysteine-rich protein with Kazal motifs
NCBI Organism
Homo sapiens
Other Product Names
Reversion-inducing cysteine-rich protein with Kazal motifs, hRECK, Suppressor of tumorigenicity 15 protein, RECK, ST15
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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