GM2A Antibody
Product Specifications
Background
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
2760
Swiss Prot
P17900
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 24-193 of human GM2A (NP_000396.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 26kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
GM2A
Positive Control 2
Rat liver
NCBI Official Name
GM2 ganglioside activator
NCBI Organism
Homo sapiens
Other Product Names
GM2A, sphingolipid activator protein 3, SAP-3, GM2 ganglioside activator, cerebroside sulfate activator protein, GM2-AP
Tested Applications
WB
Physical Properties
Liquid
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