GAMT Antibody
Product Specifications
Background
The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.
NCBI Gene ID
2593
Swiss Prot
Q14353
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human GAMT (NP_000147.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 29kDa
Fragment
IgG
Symbol
GAMT
Positive Control 2
Jurkat
Positive Control 3
HeLa
Positive Control 4
293T
Positive Control 5
Mouse liver
Positive Control 6
Rat liver
NCBI Official Name
Guanidinoacetate N-methyltransferase
NCBI Organism
Homo sapiens
Other Product Names
GAMT, PIG2, TP53I2, CCDS2, HEL-S-20
Tested Applications
WB, IF
Physical Properties
Liquid
Curated Selection
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