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ZWINT Antibody

Product Specifications

Background

This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

11130

Swiss Prot

O95229

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human ZWINT (NP_008988.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle

Purification

Affinity purification

Positive Control

293T

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=22-131

Calculated Molecular Weight

Observed: 39kDa

Fragment

IgG

Symbol

ZWINT

Positive Control 2

SW620

Positive Control 3

HepG2

Positive Control 4

Jurkat

Positive Control 5

Mouse brain

NCBI Official Name

ZW10 interactor

NCBI Organism

Homo sapiens

Other Product Names

ZW10 interactor, ZW10-interacting protein 1, Zwint-1, ZWINT

Tested Applications

WB, IF

Physical Properties

Liquid

Curated Selection

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