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NR2E3 Antibody

Product Specifications

Background

This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

NCBI Gene ID

10002

Swiss Prot

Q9Y5X4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 121-410 of human NR2E3 (NP_055064.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction, Transcription

Purification

Affinity purification

Positive Control

293T

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=22-071

Calculated Molecular Weight

Observed: 45kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

NR2E3

Positive Control 2

Raji

Positive Control 3

Mouse heart

NCBI Official Name

Nuclear receptor subfamily 2, group E, member 3

NCBI Organism

Homo sapiens

Other Product Names

NR2E3, PNR, RNR, rd7, ESCS, RP37

Tested Applications

WB

Physical Properties

Liquid

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